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Published Papers
The Structure of Hair, Muscle and Related Proteins. March 31, 1951 Authors: Linus Pauling, Robert B. Corey
| Title: |
The structure of hair, muscle, and related proteins |
| Creator: |
Pauling, Linus, 1901- |
| Contributor: |
Corey, Robert |
| Publisher: |
National Academy of Sciences |
| Date: |
1951-03-21 |
| Subject: |
Proteins -- Structure
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| Description: |
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| Type: |
Text |
| Format: |
text/plain |
| Language: |
en |
| Identifier: |
paulingcorey5-pg01.jpg |
| Source: |
Master scanned with Epson GT-10000+ flatbed scanner at 600 dpi. |
| Rights: |
http://osulibrary.orst.edu/specialcollections/coll/pauling/dna/copyright.html |
| Full Text: |
Vol. 37, 1951 CHEMISTRY: PAULING AND COREY 94.6 A.Âhese two structures accordingly might well be expected to form a protein
such as feather keratin, with a triclinic unit with a0 = 9.50 A, b0 = 34.2 A, c0 = 94.6 A, α ≅ 90°, β ≅
90°, γ ≅ 90°. It seems likely that the pleated sheets are all oriented similarly in the structure--there is no
significant indication of a unit with b0 = 68 A, corresponding to two kinds of pleated sheets, with opposite orientations.
A pleated sheet is polar: all of the C==O groups point in one direction, and the N—H groups in the opposite direction,
and in addition the side chains on one side of the sheet are arranged differently with respect to the residues than are those
on the other side of the sheet, so that an isolated sheet would be curved.¢t is interesting to speculate that this curvature
of the pleated sheets may be related to the natural curvature of the feather rachis.Å¡n example of a polar sheet in the inorganic
field is the kaolin sheet.Å“urved crystals of the clay minerals have been recently observed with use of the electron microscope,
and their curvature has been assumed to result from the polar nature of the kaolin sheets. This investigation was aided by
grants from The Rockefeller Foundation, The National Foundation for Infantile Paralysis, and The United States Public Health
Service. THE STRUCTURE OF HAIR, MUSCLE, AND RELATED PROTEINS BY LINUS PAULING AND ROBERT B. COREY GATES AND CRELLIN LABORATORIES
OF CHEMISTRY,* CALIFORNIA INSTITUTE OF TECHNOLOGY, PASADENA, CALIFORNIA Communicated March 31, 1951 It is thirty years since
x-ray photographs were first made of hair, muscle, nerve, and sinew, by Herzog and Jancke. During this period, despite the
efforts of many investigators, the photogrphs have eluded detailed in-
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