Born in Portland, Oregon on February 28, 1901, Linus Pauling is widely regarded as one of the most influential scientists of all time.

After receiving his B.S. in chemical engineering from Oregon Agricultural College (Now Oregon State University) in 1922, Pauling went to the California Institute of Technology (Caltech), where, in 1925, he took his Ph.D., majoring in chemistry with minors in physics and mathematics. With the help of a Guggenheim Fellowship, Pauling studied the fledgling discipline of quantum mechanics in Europe for a year and a half, becoming one of the first scientists to gain a strong understanding of both chemistry and the new physics. This crossing of disciplinary boundaries was a characteristic of Pauling's scientific work throughout his career. It was the fuel of Pauling's "stochastic" research method, whereby he would theorize several ideas, and discard the bad ones.

After completing his fellowship, Pauling returned to Caltech to join the chemistry faculty. In 1937 he was named chairman of the department, a position he would hold for the next twenty years. In 1939 Pauling would publish The Nature of the Chemical Bond, which remains the most frequently-cited scientific publication of the twentieth century.

In the mid-1930's, Pauling brought his knowledge of molecular structure to bear on biological molecules, particularly hemoglobin--the protein in the red blood cells. By the end of the 1940s, Pauling had determined the basic structure of proteins, the alpha-helix. He further suggested that sickle-cell anemia was a molecular disease, a hypothesis that he would later confirm with a colleague, Harvey Itano. Pauling also utilized his commitment to the U.S. government during World War II to explore practical applications of his research, chiefly through his successful development of a substitute for blood plasma. In many respects, Pauling was the godfather of modern molecular biology.

Pauling's public and political activities during the 1950s made him one of the most well-known scientists of the twentieth century. His outspoken manner on the issues of loyalty oaths, nuclear bomb tests and disarmament, as well as a host of other peace and humanitarian causes resulted in both government and media harrassment for more than a decade as well as a concomitant reputation as both a maverick and a hero.

In 1954, Pauling was awarded the Nobel Prize in Chemistry for his research into chemical bonding. Pauling's award marked the first time the Nobel Committee had awarded a prize for a body of work, rather than one hallmark discovery. Following the Nobel ceremonies in Stockholm, Pauling and his wife, Ava Helen, embarked upon a lecture tour around the world. Throughout his life, Pauling's traveling companion for the bulk of his numerous journeys was Ava Helen, to whom he was married for nearly sixty years. Only through Ava Helen's death in 1981, could Linus be separated from the person he commonly referred to as "the greatest influence on my life."

In 1963, Pauling was awarded a second Nobel Prize for his efforts to achieve nuclear disarmament, which he dedicated to Ava Helen. The genesis for the 1963 award was Pauling's 1958 submission to the United Nations of a petition signed by over 9,000 international scientists advocating the cessation of nuclear testing. Notice of Pauling's receipt of the Peace Prize was given on the same day that the United States and the Soviet Union signed a treaty agreeing to halt all above-ground nuclear explosions. Linus Pauling remains the only individual to be awarded two unshared Nobel Prizes.

After leaving Caltech, Pauling's scientific career centered around medical issues. Once again, he used his scientific knowledge to make advances in a discipline other than his original field of expertise. His research led him to develop the concept of orthomolecular medicine. Pauling also espoused the health benefits of megadoses of vitamin C. In 1973 he founded the Institute of Orthomolecular Medicine to expedite his forward-thinking research. To this day the Institute, now known as the Linus Pauling Institute of Science and Medicine and located on the campus of Oregon State University, carries on the legacy of Pauling's work in medicine and nutrition.

Linus Pauling died on August 19, 1994.

Ava Helen Miller was born the tenth of twelve children on a farm near Oregon City, Oregon on December 24, 1903. After Graduating from Salem High School, she attended Oregon Agricultural College, Where she met Linus Pauling in 1922, her teacher in a chemistry course for home economics students. She said of her first opinion of him: "He impressed me as the man among men. I listened to him with the deepest admiration and respect." They were married in Salem, Oregon on June 17, 1923. Ava Helen later wrote, "My future husband came into my life when I was still something of a child and from then on he has been not only my ideal, but my life as well."

By taking on the responsibilities of their home life and four children, Ava Helen enabled Linus to Spend his time immersed in the pursuit of science. Prior to winning his first Nobel prize, Ava Helen urged her husband to join her in the fight for peace, stating that his scientific work would not be of any value if the world was destroyed. Accordingly, Linus came to devote much of his time to "peace work."

Together, Ava Helen and Linus spoke out against the internment of Japanese-Americans during World War II. Ava Helen also stood by her husband's side as he battled Congress when denied a passport in 1952. Most significantly, the couple focused their energies on eradicating the horrors of nuclear warfare. The Paulings organized the Appeal to Stop the Spread of Nuclear Weapons, a petition signed by approximately 9,000 scientists when submitted to the United Nations in 1958. In 1961, Ava Helen and Linus arranged the Oslo Conference Against the Spread of Nuclear Weapons, a symposium on the prevention of further development of nuclear weapons. Sixty scientists from 15 countries attended. The conference's recommendations were essentially identical to the nuclear nonproliferation policies announced by President John F. Kennedy the next year.

In addition to inspiring her husband's humanitarian causes, Ava Helen was involved with several peace and civil liberties organizations herself. For three years, she served as National Vice-President of the Women's International League for Peace and Freedom. She was a board member of the Los Angeles Chapter of the American Civil Liberties Union for seven Years and a lifelong member of the Women Strike for Peace.

Ava Helen traveled throughout the world giving lectures on peace and human rights.

Among the several awards that Ava Helen Pauling received are the Janice Holland Award of the Pennsylvania chapter of Women Strike for Peace (awarded jointly with her husband), an honorary doctorate (Doctor of World Peace) from San Gabriel College, and the Ralph Atkinson Award of the Monterey County Chapter of the ACLU. This last honor reads: "...to Ava Helen Pauling, who spoke out against the internment of Japanese-Americans in 1942... challenged the inquisitorial committees of Congress in the 1950s and 1960s... and has actively supported the ACLU and its programs for half a century.

In recognition of her peace efforts, Oregon State University's College of Liberal Arts established the Ava Helen Pauling Lectureship on World Peace in 1982. The inaugural lecturer was Linus Pauling and subsequent lecturers have included Paul Warnke, Helen Caldicott, Noam Chomsky and Arun Gandhi.

Ava Helen passed away on October 7, 1981. She and Linus Pauling shared 58 wonderful years together. Whenever asked what his greatest discovery was, Linus Pauling always replied, "My wife."